Other cancer cells (observed in breast, ovarian, prostate, liver, colon, pancreatic, and head and neck squamous cell cancer) can reprogram cancer-associated fibroblasts (CAF) that express monocarboxylate transporter 4 (MCT4) to undergo aerobic glycolysis and secrete energy-rich nutrients (lactate, pyruvate, beta-hydroxybutyrate, acetate). This evidence concerns the gene SLC16A4 and cancer.