TAGLN3 and colorectal cancer: Interestingly, TAGLN2 elevated expression has been associated with progression of colorectal cancer (Zhang et al., 2010; Elsafadi et al., 2020); (c) TAGLN3 (also known as NP22 or NP25) is predominantly expressed in the nervous system (Ren et al., 1994; Depaz and Wilce, 2006).