Motif enrichment analysis showed that Gm18840 bound to the region enriched for the EWSR1-FLI1, E2F6, and ZNF263 motifs, indicating that Gm18840 might regulate the transcriptional activity of these transcription factors and contribute to myocardial ischemia–reperfusion injury. The gene discussed is FLI1; the disease is myocardial ischemia.