A series of Wilcoxon signed-rank tests indicated that more immune cells, including fibroblasts, endothelial cells, monocytes, macrophages and neutrophils, infiltrated the tumor microenvironment in patients with a higher RiskScore, whereas the low-risk group was negatively associated with activated myeloid dendritic cells, CD4+ T cells and eosinophils (Figure S1). The gene discussed is CD4; the disease is neoplasm.