In vivo experiments showed that the tumor volume and weight in the si-SOX2-OT#2 group were significantly decreased compared with the control group (all P < 0.05, Figures 5E, F), and there were significant differences in miR-143-3p and MSI2 mRNA levels in tumor tissues (all P < 0.001, Figure 5G). Here, MSI2 is linked to neoplasm.