The mRNA level of MSI2 was significantly upregulated in HCC tissue compared to adjacent normal tissues in HCC patients (P < 0.001, Figure 3I), and was positively correlated with lncRNA SOX2-OT (P < 0.001, Figure 3J), and negatively correlated with miR-143-3p (P < 0.001, Figure 3K). The gene discussed is SOX2; the disease is hepatocellular carcinoma.