In endometrioid carcinoma, PTEN mutations are associated with other mutations found in KRAS proto-oncogene, Catenin Beta 1 (CTNNB1), and PIK3CA genes and microsatellite instability, which results in short DNA sequence alterations and its ultimate replication [44, 67, 68]. Here, CTNNB1 is linked to endometrioid adenocarcinoma.