Interleukin (IL)‐4 and IL‐13 signalling pathways were also identified as distinguishing EPIT responders from nonresponders, which corresponds to our previous data demonstrating that systemic antigen‐specific Th2 cells could be detected in the peripheral circulation of EoE patients during active EoE disease.16 Here, IL4 is linked to eosinophilic esophagitis.