Finally, we found that the imbalance of 11 immune regulatory factors could predict the overall survival time of gastric cancer, including EZH2, NRP1, CD59, OsBPL1aBCL11B, BASP1, HNMT, CXCR4, ASGR2, ANXA5, CDH2. The gene discussed is CDH2; the disease is gastric cancer.