Among them Hepatic Steatosis Index (HSI) and prothrombin ratio (% PR) reflecting liver damage, urinary Na+ and Na+/K+ reflecting kidney injury, troponin for cardiac damage, and E-selectin and placental growth factor (PlGF) reflecting the vessel status were significantly different in group 2 patients as compared to group 1 (Figure 2B). The gene discussed is F2; the disease is injury.