ADIPOQ and Sepsis: Cecal ligation and puncture (CLP)-induced sepsis in obese mice results in increased expression of pro-inflammatory cytokines (TNF-α and IL-6) in visceral WAT (Tsujimura et al., 2011; Kutsukake et al., 2014) and decreased circulating adiponectin levels (Kaplan et al., 2016).