In prWAT, CLP-induced sepsis resulted in increased expression of proinflammatory (Tnf, Il6, and Ltf)-related gene expression (Figure 2A) in parallel to decreased adipogenesis (Adipoq, Pparg, Plin1, Slc2a4, Fabp4, and Lep)-, lipolytic/browning (Prkaca, Mgll, Lipe, and Prdm16)-related gene expression (Figures 2B,C), but did not exert any effects on expression of Pgc1a and lipogenic (Scd1, Acaca, and Fasn)-related genes (Figures 2C,D). The gene discussed is PRDM16; the disease is Sepsis.