As in Flanagan et al. (2018), consideration was taken of the astrocytic [Glu], reflecting the hypothesized effects of astrocytic glutamine synthetase downregulation (Perez et al., 2012) as observed in the focal sites of some epilepsies, particularly mesial temporal lobe epilepsy (MTLE) (Petroff et al., 2002; Eid et al., 2004). Here, GLUL is linked to epilepsy.