TSPAN1 and pachyonychia congenita: To further evaluate the association between the expression levels of TSPAN1, ERBB3 expression, and clinicopathologic parameters of PC including patient age, gender, grade, clinical stage of cancer (stage 1 and stage 2), TNM stage of cancer, and survival status, we drew boxplots of the hub gene expression based on the TCGA–PAAD datasets (Figure 7).