Multivariate logistic regression showed that elderly (OR 1.017, 95% CI 1.005–1.030; p value = 0.004), female (OR 1.739, 95% CI 1.351–2.238; p value < 0.001), lower levels of EF (OR 0.985, 95% CI 0.976–0.994, p value = 0.001), elevated levels of NT-proBNP (OR 1.168, 95% CI 1.118–1.222; p value < 0.001) and CRP (OR 1.008, 95% CI 1.003–1.012; p value = 0.001), and low rate of use of RAS inhibitors (OR 0.698, 95% CI 0.545–0.893, p value = 0.004) were associated with increased risk of CI-AKI among patients with HF (Table 3). This evidence concerns the gene NPPB and hydrops fetalis.