While the role of mir-7025 in the context of retinopathy requires investigation, the only gene detected as down-regulated in OIR retinas relative to normoxic controls at all three examined time-points was Pcp4. Encoding Purkinje Cell Protein 4, Pcp4 expression has been reported in ganglion, amacrine and horizontal cells35. The gene discussed is PCP4; the disease is retinal disorder.