We found significantly increased BMI1 transcript levels in the primary GC tissue classified as grade G3 (p = 0.011) and counterpart histopathologically confirmed disease-free margin tissue (p = 0.026, respectively) in the carriers of the T/T versus C/C genotypes but not for the carriers of the C/T versus C/C genotypes (p = 0.056, p = 0.11, respectively) (Fig. 1A, B). The gene discussed is BMI1; the disease is gastric cancer.