TRERF1 and non-small cell lung carcinoma: As 100nM of RAPA and 2.5μM of SAHA had modest effects on viability in the two NSCLC cell lines for 24 hours (Figure 1), NSCLC cells were treated with RAPA (100nM) and SAHA (2.5μM) for 24 hours and subsequently irradiated cells with different dose of γ-irradiation.