In conformity with pro-survival autophagy modulated by OH·, resistance to cisplatin-induced cell death, as well as the overexpression of Atg3 and Atg7 in human lung cancer cells cultured with cisplatin was repressed by pre-incubation the cells with deferoxamine (Figs. 5a and b and 6). The gene discussed is ATG7; the disease is lung cancer.