CHIT1 and amyotrophic lateral sclerosis: Although chitin is not expressed in human cells, CHIT1 levels are elevated in serum and cerebrospinal fluid (CSF) in various diseases including Gaucher disease, idiopathic pulmonary fibrosis, sarcoidosis, chronic obstructive pulmonary disease and neurodegenerative/-inflammatory diseases such as Alzheimer’s disease (AD), frontotemporal dementia, multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) [7, 12–24].