CXCL9 (p = 0.027), CXCL10 (p < 0.001), CXCL11 (p = 0.002) and CXCL13 (p < 0.001) were significantly up-regulated in tumor tissues compared with tumor-adjacent tissues, while the expression of CXCL12 (p = 0.149) was down-regulated. The gene discussed is CXCL12; the disease is neoplasm.