HOOK3 and non-small cell lung carcinoma: Then, we noticed that HOOK3 was significantly upregulated in the CR-NSCLC cells (Fig. 4G) and clinical tissues (Fig. 4H), comparing to the CS-NSCLC cells and tissues, and the Pearson correlation analysis results supported that miR-194-5p negatively correlated with HOOK3 mRNA in the NSCLC tissues (Fig. 4I).