Mice with a tumor volume of over 20 mm3 were intravenously injected with PBS or 125 nmol free Cur, Cur@α-NTP-LNs, or peptide equivalent α-NTP-LNs on day 13, and the intravenous injection was repeated every other day for 5 times (Fig. 5a). This evidence concerns the gene HOXA7 and neoplasm.