Specifically, included CPGs [30–35] were non-concordant for the recommendations to perform baseline blood chemistry (sodium, potassium, creatinine) (ACC-7), fasting blood glucose level test (ACC-8), fasting lipid profile test (ACC-9), serum hemoglobin or haematocrit level test (ACC-12), serum calcium level test (ACC-13), serum uric acid level test (ACC-14), and urine testing for albumin: creatinine ratio (ACC-15), in all adults newly diagnosed with hypertension, as specified in the 2017 ACC/AHA guideline [22]. The gene discussed is ALB; the disease is Hypertension.