SACM1L and infection: In contrast, the loss of SAC1 reduced the delivery of lysosomal enzymes to Salmonella-containing autophagosomes, as reflected by the lower percentage of bacteria with pepstatin A (Figure 3F) as well as the lower percentage of LC3+pepstatin A+Salmonella in SACM1L KO cells (14%) than in WT cells (21%) by 2 h post-infection (Figure 3G).