JUN and infection: Interestingly JUN (c-JUN; AP-1, P05412) was highly upregulated in response to YopJC172A Y. pseudotuberculosis in comparison to wild-type infection (fold change, FC = 23), indicating a potential role for this transcriptional factor in mediating the host response to LPS and specific effects on PGE2 (Fig. 3F; see also Table S1).