BCL2 and acute myeloid leukemia: Also, with subsequent studies done by Kulsoom et al., (2018) which showed that Expression of Bax and Bcl-2 does not differ significantly among AML patients in terms of remission, relapse, resistance, overall survival, and disease-free survival suggest that there is no significant association between the expression of Bax and Bcl-2 and their ratio with clinical response, or with 1-year DFS and OS.