A combination of both P16INK4a and Ki-67 immunohistochemical markers were applied to post-therapy cases of cervical cancer to detect residual tumour by Desai et al., 2021 with an accuracy of 82.86% (95%CI: 66.4- 93.4) for P16INK4a and 100% (CI:90.0-100.0) for Ki-67 stain. This evidence concerns the gene MKI67 and neoplasm.