CDKN2A and cervicitis: (χ2= 91.32*, p<0.0001) (Table 2) The diagnostic value of Ki-67 and P16 INK4a immuno-histochemical markers on cervical biopsy had been evaluated by calculating the Sensitivity, Specificity, Positive predictive value (PPV) and Negative Predictive Value (NPV) of the cervical lesion.