Hyperglycemia in diabetes not only impairs the sensory neurons but also the Schwann cell function which leads to myelin disruption, impaired axon conduction, and compromised regeneration in diabetic neuropathy via deregulation of different targets such as MAPK, p75 neurotrophin receptor (NTR), and β‐nerve growth factor (NGF) as well as neurotrophic factor‐3 (NT‐3).[206]. Here, NGF is linked to diabetes mellitus.