In kidney disease, Naito et al. [31] found that BRG1 increased the transcription of TNF-α and MCP-1 in renal ischaemia, and Liu et al. [32] demonstrated that endothelial-specific deletion of BRG1 alleviates renal injury in unilateral ureteral obstruction (UUO) mice. The gene discussed is SMARCA4; the disease is Ureteral obstruction.