COL2A1 and scoliosis: Approximately 60% of Col2a1-Cre; Adgrg6f/f mice exhibited scoliosis at P20 (52.1%; n = 23), P40 (60.8%; n = 23), and P120 (58.8%; n = 17) (Figure 2I, K, L), with the apex of the curvature centered at thoracic vertebrae (T)8 and T9 (Figure 2J).