ADGRG6 and scoliosis: Ablation of Adgrg6 during perinatal development in ATC; Adgrg6f/f mice showed no evidence of scoliosis when assayed at P20 (0.0%; n = 8), while a single ATC; Adgrg6f/f mutant mouse (12.5%; n = 8) showed late-onset scoliosis when assayed at P180 with a curve of 23.8° (Figure 6D–F, J).