IL6 and infection: Specifically, compared with control KD with mock infection, RSV induced SNAI1, IL6, MMP9, FN1, and VIM in control KD cells by 10.2 ± 0.93-fold (P = 3.31E-10), 32.4 ± 2.9-fold (P = 1.35E-10), 101.8 ± 6.81-fold (P = 6.07E-12), 6.4 ± 0.27-fold (P = 5.95E-13), and 3.99 ± 0.34-fold (P = 1.37E-09), respectively; with XBP1 KD, these inductions were downregulated to 4.92 ± 0.46-fold (P = 1.91E-07), 19.4 ± 1.43-fold (P = 1.92E-06), 45.1 ± 5.64-fold (P = 2.26E-08), 4.0 ± 0.3-fold (P = 5.23-08), and 3.0 ± 0.2-fold (P = 1.31E-04), respectively.