Feng et al. have indicated that the LncRNA BACE1 (95% CI: 0.553–0.781, p = 0.003) is elevated in the plasma in patients with Alzheimer's disease (AD) and has high specificity (88%) for AD; therefore, LncRNA BACE1 may be a potential candidate biomarker for predicting AD.19 The gene discussed is BACE1; the disease is early-onset autosomal dominant Alzheimer disease.