We set the cutoff of the signal binding normalized scores (in the range of 0–1000) to 350 and identified promyelocytic leukemia (PML), cyclin T2 (CCNT2) and MYC-associated zinc finger protein (MAZ) as binding to both the +157 enhancer and the promoter of the VEGFA gene (Supplementary Table S2; Supplementary Figure S6A and B). Here, PML is linked to leukemia.