Expression of EMT markers, such as Slug, Snail1, Twist1 and N-cadherin was found to be significantly higher in HNSCC tissues compared to adjacent normal tissues, both at the mRNA transcript (Figure 2A; p < 0.001) and protein levels (Figure 2B; p < 0.01). This evidence concerns the gene SNAI2 and head and neck squamous cell carcinoma.