Overexpression of hypoxia-inducible factor (HIF-1α), histone deacetylase (HDAC), and carbonic anhydrase IX (CAIX), as well as constitutive activation of the Akt/NF-kB pathway, have been implicated in carcinoid tumorigenesis [2–4]. This evidence concerns the gene NFKB1 and carcinoid tumor.