These differences included several genes of antiviral immune response pathways such as HLA-B, HLA-C, HLA-DQB1 IFI16, IFITM3, CD74 (MHC class II transporter), tumor suppressor genes EGF-containing fibulin extracellular matrix protein (EFEMP1), and the transcription factor early growth response 1 (EGR1), all upregulated in BA tumor versus WA tumor, and downregulated in BA TAS versus WA TAS. The gene discussed is IFI16; the disease is neoplasm.