Pathways that were significantly downregulated in TAS of BA patients (p < 0.05) but not significant in the tumor comparison included antiviral immune response pathways such as dendritic cell maturations, B cell receptor signaling, natural killer cell signaling, mTOR signaling, antigen presentation and regulation of eIF4 and p70S6K signaling (Figure 3D, Supplementary Dataset 3; Supplementary Table 3C). This evidence concerns the gene MTOR and breast angiosarcoma.