In the model mice bearing both PSMA-positive (22Rv1) and negative (PC3) tumors, the uptake of [68Ga]PSMA-11 in the 22Rv1 tumor (2.7 ± 0.3 %ID/g) was six-fold greater than the PC3 tumor (0.5 ± 0.1 %ID/g), demonstrating that [68Ga]PSMA-11 bound selectively to the PSMA-positive, PSMA-rich tumors (P = 0.0030, t(df) = 6.430(4)). This evidence concerns the gene FOLH1 and neoplasm.