SLC30A10 and Rapid-onset dystonia-parkinsonism: The Thr95Ile variant occurs in the third of six transmembrane domains of the SLC30A10 protein72, the same domain affected by a previously reported loss-of-function variant causing HMNDY1 (hypermanganesemia with dystonia 1), Leu89Pro (rs281860284)56 (Fig. 6).