In MCF7 cells, this increased resistance was accompanied by the induction of some ABC transporters frequently responsible for chemoresistance in breast cancer (i.e., ABCB1, ABCC1, and ABCG2) (Fig. 1F), the increased expression of the anti-apoptotic proteins BCL-2 and Survivin (Fig. 1G), which were not observed in T47D cells over-expressing ETV7 (Supplementary Fig. 1G, J). Here, BIRC5 is linked to breast cancer.