We obtained the risk score of each case with colon cancer; risk score = (0.46121 × expression of ULK3) + (0.650715 × expression of ATG101) + (1.521474 × expression of MAP1LC3C) + (0.641122 × expression of TSC1) + (0.243022 × expression of DAPK1) + (-0.17015 × expression of SERPINA1). This evidence concerns the gene SERPINA1 and malignant colon neoplasm.