In the high-risk patients, antigen presentation cells (aDCs, DCs, and pDCs), B cells, CD8+T cells, TIL (tumor-infiltrating lymphocyte), macrophages, mast cells, T helper cells, Tfh cell, TIL (tumor-infiltrating lymphocyte), and T cells regulatory (Tregs) were significantly higher than in low-risk patients (Figure 10A). Here, CD8A is linked to neoplasm.