RNASEL and lung carcinoma: To study SARS-CoV-2 infections in a cell line with a robust innate immune response we transduced parental (WT) and RNase L knockout (RL-KO) A549 lung carcinoma cell lines (Burke et al. 2019) with an ACE2-encoding lentivirus to make them permissive to SARS-CoV-2 infection.