For instance, MALAT1-m6A modifications generated by the METTL3-METTL14 complex are important to the metastatic ability of esophageal cancer cells (ESCCs), but silencing METTL3 cannot recapitulate the phenotypes of impaired migration observed in MALAT1-Δm6A cells. Here, MALAT1 is linked to esophageal cancer.