ADGRE5 and infection: To evaluate the effect of physiological levels of SteD on surface levels of CD97, MutuDCs were examined by flow cytometry after infection with either wild type (WT) S. Typhimurium, a SPI-2 T3SS mutant (ΔssaV; unable to translocate effectors through the SPI-2 T3SS), an ΔsteD mutant or the complemented strain (ΔsteD + psteD).