The intensity of immunohistochemical expression of PAX2 in normal fimbriae was 1.64x104 ± 0.13x104 in 20,000 μm2 area of tissue and decreased significantly in tumor limited to the fimbria (early stage) (P<0.0001) and in tumors metastasized to distant organs (late stage) (P < 0. The gene discussed is PAX2; the disease is neoplasm.