It has been reported that urine of healthy dogs contains low concentrations of albumin (3.1 ± 1.4 mg/dl) and a high concentration of uromodulin (11.9 ± 2.3 mg/dl), whereas the urine samples of dogs with CKD showed the opposite pattern, where the level of albumin increased to 26.6 mg/dl, but the concentration of uromodulin decreased to near 0 mg/dl [13]. Here, UMOD is linked to chronic kidney disease.