Mice with xenografted tumor size that grew up to 30–70 mm3 were intraperitoneally given PBS, 5 mg/kg cisplatin, or 400 μg N-mAb on day 0 and PBS, 5 mg/kg cisplatin or 200 μg anti-GITR mAb on day 7 (Fig. 5a). Here, TNFRSF18 is linked to neoplasm.