APC and mantle cell lymphoma: To test whether SENP1 knockdown can induce apoptosis in MCL cells, we detected the apoptosis of stable Jeko-1 cells with shSENP1-2 or shSENP1-3 and stable Mino cells with shSENP1-1 or shSENP1-3 by Annexin V-APC and PI double staining.