Cell cycle (NES = 2.31, P = 0.000), pancreatic cancer (NES = 1.82, P = 0.017), p53 signaling pathway (NES = 2.10, P = 0.0004), pathogenic Escherichia coli (NES = 2.08, P = 0.000), and small cell lung cancer (NES = 1.85, P = 0.0008) signaling pathways were enriched in the high-risk group. This evidence concerns the gene TP53 and familial pancreatic carcinoma.