In order to assess the prognostic value of 82 FAM83D-related immunomodulators, we firstly identified 4 genes (SLAMF6, IL10RB, MICB and TNFSF4) in train set by univariate COX analysis that were significantly related to the prognosis of HCC (Figure 8a). This evidence concerns the gene SLAMF6 and hepatocellular carcinoma.