In order to assess the prognostic value of 82 FAM83D-related immunomodulators, we firstly identified 4 genes (SLAMF6, IL10RB, MICB and TNFSF4) in train set by univariate COX analysis that were significantly related to the prognosis of HCC (Figure 8a). The gene discussed is MICB; the disease is hepatocellular carcinoma.