CD4 and cancer: In LUAD, MALAT1 mRNA level was related to CD8 + T cell, CD4 + T cell, B cell, neutrophil cell, DC cell, Tregs cell, NK cell, Mast cell, cancer-associated fibroblast, common lymphoid progenitor, common myeloid progenitor, endothelial cell, eosinophil, hematopoietic stem cell, MDSC, and T-cell follicular helper cell infiltration (Figure 3).