MMP1 and systemic sclerosis: There areconflicting data on MMPs expression in scleroderma.While some researchers reported downregulation of MMP1in scleroderma patients with increases in the levels of tissueinhibitor of MMP (TIMPs) (36), other studies reported theincreased expression of MMP1 in SSc fibroblasts comparedto healthy fibroblasts (37).